Niacinamide is a skin care product that many people know about. So can niacinamide whiten your skin? How long does it take for niacinamide whitening to take effect? Can niacinamide whiten your skin? Niacinamide does have a whitening effect. Niacinamide can downregulate the transport of melanosomes from melanocytes to keratinocytes without inhibiting tyrosinase activity or cell proliferation, thereby affecting skin pigmentation. It can also interfere with the cell signaling pathway between keratinocytes and melanocytes and reduce melanin production. So theoretically, it can reduce the production of melanin and thus play a whitening role. However, babies with sensitive skin and red blood streaks should not use it. How long does it take for niacinamide to take effect? The duration varies from person to person, but generally it takes one to two months for noticeable results to appear. Niacinamide does have a whitening effect. Niacinamide can downregulate the transport of melanosomes from melanocytes to keratinocytes without inhibiting tyrosinase activity or cell proliferation, thereby affecting skin pigmentation. It can also interfere with the cell signaling pathway between keratinocytes and melanocytes and reduce melanin production. So theoretically, it can reduce the production of melanin and thus play a whitening role. However, whether the effect is obvious depends on whether the ingredients are sufficient, and generally it takes one or two months for the whitening effect to appear. In addition to whitening, niacinamide can also repair the damaged stratum corneum lipid barrier and improve skin resistance. There are also some effects that may be overlooked by people, that is, the deep water-locking effect of niacinamide. Therefore, skin care products containing niacinamide have extremely strong water-locking and moisturizing effects. When the concentration of nicotinamide was 0.25 and 1.25 mg/ml, the movement rate of melanosomes in melanocytes increased significantly (P<0.05), and the density of melanosomes in cells decreased with the increase of nicotinamide concentration. Conclusion Nicotinamide participates in the transport process of melanin and can accelerate the movement rate of melanosomes in melanocytes, indicating that nicotinamide has a regulatory effect on calcium pumps, cell motor protein Dynein expression and melanosome movement, and the concentration is an important regulatory factor. Niacinamide has a whitening effect, but how long it takes to be effective depends on the individual. |
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