What is the whitening principle of niacinamide? Comprehensive understanding of the whitening mechanism of niacinamide

What is the whitening principle of niacinamide? Many sisters may know that niacinamide can whiten the skin, but they are not clear about the principle of niacinamide whitening. So, let’s learn about the whitening mechanism of niacinamide today.

What is the whitening principle of niacinamide?

Niacinamide has a whitening effect because it can inhibit the deposition of melanin and block the transfer of melanin to surface cells. It can also accelerate the shedding of keratin containing melanin, reduce the yellowing of protein after glycation, and reduce the size and number of spots.

Detailed explanation of the whitening mechanism of niacinamide

1. Accelerate metabolism and promote the shedding of keratinocytes containing melanin

Skin cells need sufficient energy to complete their daily physiological functions, such as producing new cells, synthesizing collagen, producing fat and protein, and synthesizing DNA. Aging and other reasons often cause a decrease in the energy of cell activity, resulting in slower cell renewal, excessive pigmentation, reduced skin moisture, uneven cuticles, etc. Because niacinamide has a small molecule, it can be directly absorbed by cells. Niacinamide can maintain the energy balance of the skin, while restoring cell energy and accelerating collagen synthesis, thereby avoiding excessive melanin deposition caused by low oil content and thinning of the stratum corneum. In addition, niacinamide promotes the shedding of keratinocytes containing melanin by accelerating skin renewal.

2. Act on the melanin that has already been produced and reduce its transfer to the surface cells

Because only when melanin is delivered to keratinocytes will the skin appear darker. Niacinamide acts on the melanin that has already been produced, effectively inhibiting the transfer of about 35% to 40% of melanin from melanocytes to keratinocytes, thereby reducing excessive pigmentation. Clinical trials have shown that using a moisturizer containing niacinamide can significantly reduce the area and number of brown spots on the skin, and the lightening of the color of the spots can be seen with the naked eye. This is the most important reason why niacinamide acts as a whitening agent.

3. Promote the synthesis of epidermal protein and improve skin texture

Niacinamide can promote the synthesis of epidermal protein, enhance the skin's own defense ability, and increase the skin's moisture content. Therefore, niacinamide is also widely used in anti-aging products.

Is Niacinamide Harmful to the Skin?

Niacinamide is not harmful to the skin, on the contrary it is beneficial. Niacinamide has a whitening effect because it can inhibit the deposition of melanin and block the transfer of melanin to surface cells. It can also accelerate the shedding of keratin containing melanin, reduce the yellowing of protein after glycation, and reduce the size and number of spots. Niacinamide can promote dermis microcirculation, maintain skin moisture (that is, moisturizing) and reduce free radical damage to the skin. Therefore, it can slow down skin aging and enhance skin defense, and is also widely used in anti-aging products.

Conclusion: Nicotinamide participates in the transport process of melanin and can accelerate the movement rate of melanosomes in melanocytes, indicating that nicotinamide has a regulatory effect on calcium pumps, cell motor protein Dynein expression and melanosome movement, and the concentration is an important regulatory factor.