What is the difference between oligopeptide stock solution and polypeptide stock solution? What is polypeptide and what is oligopeptide?

A classification of polypeptides, with a molecular weight generally below 1000 Daltons, also known as small peptides, oligopeptides, low-molecular-weight peptides or small molecule active peptides, generally composed of 4-10 amino acids. Those exceeding this are called polypeptides, and polypeptides with more than 50 amino acids are called proteins. So, what is the difference between oligopeptide stock solution and polypeptide stock solution?

What is the difference between oligopeptide stock solution and polypeptide stock solution?

1. Structural differences

Amino acids are the smallest building blocks of proteins. A peptide composed of two amino acids is called a dipeptide, and so on. Peptides of 10 or less are called oligopeptides, and peptides of 11 or more are called polypeptides. The molecular weight of collagen polypeptides is around 1000-3000D, while the molecular weight of oligopeptides is less than 1000D.

2. Difference in absorption

Compared to polypeptides, oligopeptides are relatively small molecules. No need for digestion, just absorbed directly. Oligopeptides with small molecular weight can have higher skin permeability than polypeptides, are more easily absorbed by human skin, and can be 100% absorbed by the human body. At the same time, as the molecular weight is reduced to a certain extent, the biological activity undergoes a qualitative leap. The smaller the molecular weight of the peptide, the shorter the "amino acid chain", and the easier it is to be absorbed and utilized by the human body.

3. Differences in function

Oligopeptides have a carrier effect. Other nutrients of human food can be carried on its body and transported to human cells and tissues. It becomes a transportation tool in the human body, transporting various trace elements to various parts of the body. It has extremely strong activity and diverse physiological functions. Peptides mainly control the growth, development, immune regulation and metabolism of the human body, keeping the human body in a state of balance.

What is Peptide

It is generally believed that a peptide composed of 10 to 100 amino acid residues is called a polypeptide. Their molecular weight ranges from 1000 to 10,000 (Dalton) and are not easily absorbed by the skin. For example: EGF, which is composed of 53 amino acids and has a molecular weight of more than 60,000, cannot be absorbed by the skin and can only act on the skin surface. At the same time, cytokines such as EGF and bFGF are not currently permitted ingredients for cosmetics.

What is oligopeptide

Peptides composed of 2 to 10 amino acid residues are called oligopeptides (small molecule active peptides). Their molecular weight is usually below 1000 and they are easily absorbed by the skin to exert their active effects, such as "hexapeptide", "glutathione", etc. Oligopeptides overcome many of the shortcomings of previous polypeptides. At the same time, they comply with relevant regulations for skin care products and can be legally registered. They have become an inevitable choice for repair products.